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In support of this, we found that aspects of cytoplasmic endogenous SIRT7, including protein expression, stability, and phosphorylation, were much more sensitive to GSK3 inactivation than the nuclear fraction (Supplementary Fig

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the present invention also provides nucleic acids encoding these proteins, which proteins and nucleic acids are associated with the pathology of malaria infections, and which may be used as vaccines or other prophylactic treatments for the prevention of malaria infections, and/or in diagnosing and treating the symptoms of patients who suffer from malaria and associated diseases